Engineering next-generation RNA therapeutics inspired by extracellular vesicles
Sébastien Jauliac received a M2 degree from Pasteur Institute, University Pierre et Marie Curie, Paris, France in 1996 and a PhD from University Pierre et Marie Curie, Paris, France in 1999. He conducted his post-doctoral research in the laboratory of Prof. Alex Toker in the Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, US. His first faculty appointment was as INSERM Avenir Scientist at IUH, Paris, France in 2004, where he was promoted to Principal Investigator in 2006. Sebastien Jauliac works at the IRSL in Paris.
Research Assistants
Frédéric Guaddachi is a research assistant in the lab
Research Fellow
Guénolé Tossou received his Bachelor's degree through the Magistère de Génétique at Université Paris Cité. His Ph. research focuses on extracellular vesicle biology, regulatory RNAs, and the development of combinatorial RNA therapeutic strategies for aggressive cancers. He is the first author of our recent publication in Molecular Therapy. Guénolé is supported by a doctoral fellowship from the French Ministry of Higher Education and Research (MESR).
Students
Ninon Lippens is currently a student in the Magistère de Génétique at Université Paris Cité. She will join in january 2027 the Jauliac Lab to investigate extracellular vesicle biology, regulatory RNAs, and combinatorial RNA therapeutic strategies for aggressive cancers.
Harris Asare is a Breast Surgery resident and is currently completing his Master's degree (MSc). His research focuses on the development of three-dimensional patient-derived tumor organoid models to study aggressive breast cancers and support the preclinical evaluation of novel RNA-based therapeutic approaches.
Collaborators
Stéphane Brunet is an INSERM Senior Researcher whose research combines cell biology, tissue architecture, and advanced three-dimensional models to better understand cancer biology. In the Jauliac Lab, he develops patient-derived tumor organoid models for translational cancer research.
Laurence Cahen-Doidy is Head of the Breast Surgery Unit at Saint-Louis Hospital (AP-HP) and a clinician-scientist affiliated with INSERM and Université Paris Cité. Her research focuses on translational breast cancer research, with particular interests in precision oncology, predictive biomarkers, and the clinical translation of extracellular vesicle-based approaches.
Lauriane Goldwirt is a Hospital Pharmacist and Head of the Biological Pharmacology Unit at Saint-Louis Hospital (AP-HP). Her expertise in cancer pharmacology, pharmacokinetics, and translational oncology supports the development and preclinical evaluation of innovative therapeutic strategies for cancer.
Alumini
Marjorie Fougère (PhD, 2008)
Sophie Balmer (M2, 2009)
Benoît Gaudineau (PhD, 2010)
Lorelei Naudeau (PhD, 2014)
Lucie Coillard (PhD, 2014)
Livia Camargo (PhD, 2016)
Nadia Ourari (Master 2, 2019)
Maelle Rallu (M2, 2020)
Manon Paul (Physician student, 2021)
Babette Beher (Master, 2021)
Eloïse Meyer (Master, 2022)
Emilie Ouanounou (Sup Biotech, 2022)
Samuel Sesay ( ESTBA, 2026)
Hélène Le, Pabic (Post-doc, 2008)
Nadège Girardot (Post-doc, 2007)
Alexandre Montanede (2022-2024)
David Bergerat (2016-2019)