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Engineering next-generation RNA therapeutics inspired by extracellular vesicles
Introduction
Deciphering cancer complexity to develop next-generation RNA therapeutics
Aggressive cancers are driven by complex molecular networks that cannot be efficiently addressed by single-target approaches.
Our laboratory investigates cancer vulnerabilities and develops innovative therapeutic strategies inspired by extracellular vesicles and regulatory RNA biology.
Research Overview
Extracellular Vesicles
Extracellular Vesicles
Extracellular Vesicles as natural carriers of therapeutic information
Extracellular vesicles (EVs) are key mediators of intercellular communication, capable of transferring functional molecular cargo between cells.
We investigate how EV-associated regulatory RNAs influence cancer cell behavior and how these biological properties can inspire new therapeutic approaches.
RNA Therapeutics
RNA Therapeutics
Combinatorial RNA strategies to target cancer networks
Cancer progression involves multiple interconnected pathways.
We explore how rational combinations of regulatory RNAs can simultaneously modulate several cancer-associated processes.
Cancer Vulnerabilities
Cancer Vulnerabilities
Identifying molecular vulnerabilities in aggressive cancers
Understanding the mechanisms that sustain cancer progression is essential for developing new therapeutic strategies.
We study the biological processes controlling tumor growth, invasion and adaptation to identify new opportunities for intervention.
From Discovery to Translation
Research Impact
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